Endocrine Abstracts

Introduction: Opioids are commonly used for the treatment of pain, and their effects on the HPA (hypothalamic pituitary adrenal) axis may be under-recognised. In the present, a few non-systematic studies have investigated the effects of opioids on the HPA axis, but results have been conflicting. To our knowledge, there is only another case report of secondary adrenal insufficiency due to tramadol therapy, resulted in suppression on the HPA axis. We present the case of a 79 yea...

Background: PCOS patients associate an increased risk of glucose metabolism abnormalities. Although Hb A1c was suggested as a good diagnostic test for prediabetes/diabetes, in PCOS patients its diagnostic value could be inferior to OGTT as previously suggested. Aim of the study was to evaluate which are the clinical and paraclinical parameters associated with impaired glucose tolerance (IGT) in order to identify the profile of the patients that will benefit from OGTT.<p cl...